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Cell cycle-uncoupled cytokinesis in AmiA:myosin II double KO cells.
Species name:Dictyostelium discoideum
National Institute of Advanced Industrial Science and Technology Taro Uyeda
The mutant cellular slime mold Dictyostelium discoideum lacking myosin II and AmiA cannot perform cell cycle-dependent cytokinesis. These cells fragment by traction-mediated, cell cycle-uncoupled method of division (cytokinesis C). These cells express GFP-histone to visualize nuclear division. Note that nuclear division, synchronous in each multinucleate cell, is not followed by cell division.
Genetic and morphological evidence for two parallel pathways of cell cycle-coupled cytokinesis in Dictyostelium. J. Cell Sci., 115: 2241-2251.
Variations on a Theme - the Many Modes of Cytokinesis. Curr. Opin. Cell Biol., 16:55-60